This chapter aims to develop a method of water quality determination using fuzzy logic and compare it with other traditional methods with the purpose to optimize the existing analytical techniques towards the engineering problem of improving the quality of water. Water quality index is based on three steps: selection of parameters, determination of the curve for each parameter, and aggregation with mathematical expression. The water quality assessment depends mainly on the aggregation of information on water quality parameters at different times and places. The water quality index by fuzzy logic can be used as a comprehensive tool for water quality assessment by agencies, managers and research institutions according to their environmental realities and purposes, with minor modifications. The chapter applies the fuzzy logic methodology as an optimization technique to a case study.