脂质过氧化
神经病理性疼痛
GPX4
周围神经损伤
医学
过氧化脂质
脊髓
谷胱甘肽
线粒体
药理学
氧化应激
坐骨神经
麻醉
病理
内分泌学
谷胱甘肽过氧化物酶
化学
超氧化物歧化酶
生物化学
精神科
酶
作者
Yue Guo,Jingyi Du,Cuicui Xiao,Ping Xiang,Yifan Deng,Ziqing Hei,Xiang Li
摘要
The spinal ferroptosis-like cell death was involved in the development of neuropathic pain resulted from peripheral nerve injury, and inhibition of ferroptosis by liproxstatin-1 could alleviate mechanical and thermal hypersensitivities. This knowledge suggested that ferroptosis could represent a potential therapeutic target for neuropathic pain.
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