医学
毒性
重症监护医学
免疫疗法
临床实习
免疫学
内科学
家庭医学
免疫系统
作者
Yael Zlotnikov Klionsky,Alexa Meara,Pankti Reid
标识
DOI:10.1016/j.rdc.2024.01.005
摘要
Cancer immunotherapy is revolutionary for survival but has complications due to immunogenicity with unpredictable and potentially long-lasting autoimmune side effects known as immune-related adverse events (irAEs). Currently, treatment beyond corticosteroids can be complicated by the diversity of providers who are needed across a variety of clinical settings to manage irAEs. We outline the role of critical players in the management of irAEs, discuss the current limitations that exist, and propose various methodologies that can be adapted across clinical settings to tackle these needs. We aim to better understand who can be affected by irAEs and tailor diagnostics and therapeutics appropriately.
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