Home-made optical tweezers for biomedical applications

Abstract Optical tweezers has been built with confocal fluorescence microscope as based detection. Microsphere particles and 780 nm fluorescence dye molecules are used in our demonstration. With the combination between these two particles, light focusing and particle manipulation can be performed simultaneously. The experimental results show that the tweezers can trap and move particles and even rotate the clusters of dye molecules sharply. We aim to apply our tweezers to biomedical applications such biological samples in the near future.