余辉
发光
纳米点
持续发光
纳米技术
材料科学
激子
光致发光
磷光
光电子学
光化学
化学
物理
光学
荧光
天文
伽马射线暴
热释光
量子力学
作者
Guang‐Song Zheng,Cheng‐Long Shen,Chunyao Niu,Qing Lou,Tianci Jiang,Pengfei Li,Xiaojing Shi,Run‐Wei Song,Yuan Deng,Chunxiao Lv,Kaikai Liu,Jinhao Zang,Zhe Cheng,Lin Dong,Chongxin Shan
标识
DOI:10.1038/s41467-024-46668-z
摘要
It remains a challenge to obtain biocompatible afterglow materials with long emission wavelengths, durable lifetimes, and good water solubility. Herein we develop a photooxidation strategy to construct near-infrared afterglow carbon nanodots with an extra-long lifetime of up to 5.9 h, comparable to that of the well-known rare-earth or organic long-persistent luminescent materials. Intriguingly, size-dependent afterglow lifetime evolution from 3.4 to 5.9 h has been observed from the carbon nanodots systems in aqueous solution. With structural/ultrafast dynamics analysis and density functional theory simulations, we reveal that the persistent luminescence in carbon nanodots is activated by a photooxidation-induced dioxetane intermediate, which can slowly release and convert energy into luminous emission via the steric hindrance effect of nanoparticles. With the persistent near-infrared luminescence, tissue penetration depth of 20 mm can be achieved. Thanks to the high signal-to-background ratio, biological safety and cancer-specific targeting ability of carbon nanodots, ultralong-afterglow guided surgery has been successfully performed on mice model to remove tumor tissues accurately, demonstrating potential clinical applications. These results may facilitate the development of long-lasting luminescent materials for precision tumor resection.
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