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Sorbs2 Modulation of BK Channels in Arterial Myocytes: Implications for Diabetes

离子通道病 医学 图书馆学 内科学 计算机科学
作者
Luis F. Santana,Manuel F. Navedo
出处
期刊:Circulation Research [Lippincott Williams & Wilkins]
卷期号:134 (7): 872-874
标识
DOI:10.1161/circresaha.124.324241
摘要

HomeCirculation ResearchVol. 134, No. 7Sorbs2 Modulation of BK Channels in Arterial Myocytes: Implications for Diabetes No AccessEditorialRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessEditorialRequest AccessFull TextSorbs2 Modulation of BK Channels in Arterial Myocytes: Implications for Diabetes L. Fernando Santana and Manuel F. Navedo L. Fernando SantanaL. Fernando Santana Correspondence to: L. Fernando Santana, PhD, Department of Physiology and Membrane Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616. Email E-mail Address: [email protected] https://orcid.org/0000-0002-4297-8029 Department of Physiology and Membrane Biology (L.F.S.), School of Medicine, University of California, Davis, CA. and Manuel F. NavedoManuel F. Navedo https://orcid.org/0000-0001-6864-6594 Department of Pharmacology (M.F.N.), School of Medicine, University of California, Davis, CA. Originally published28 Mar 2024https://doi.org/10.1161/CIRCRESAHA.124.324241Circulation Research. 2024;134:872–874This article is a commentary on the followingSorbs2 Deficiency and Vascular BK Channelopathy in DiabetesFootnotesFor Sources of Funding and Disclosures, see page 874.The opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.Correspondence to: L. Fernando Santana, PhD, Department of Physiology and Membrane Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616. Email lfsantana@ucdavis.eduREFERENCES1. Sun X, Lee H, Lu T. Sorbs2 deficiency and vascular BK channelopathy in diabetes mellitus.Circ Res. 2024; 134:858–871. doi: 10.1161/CIRCRESAHA.123.323538LinkGoogle Scholar2. Spassova MA, Hewavitharana T, Xu W, Soboloff J, Gill DL. A common mechanism underlies stretch activation and receptor activation of TRPC6 channels.Proc Natl Acad Sci USA. 2006; 103:16586–16591. doi: 10.1073/pnas.0606894103CrossrefMedlineGoogle Scholar3. Gonzales AL, Yang Y, Sullivan MN, Sanders L, Dabertrand F, Hill-Eubanks DC, Nelson MT, Earley S. A PLCgamma1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.Sci Signaling. 2014; 7:ra49. doi: 10.1126/scisignal.2004732CrossrefMedlineGoogle Scholar4. Bulley S, Fernandez-Pena C, Hasan R, Leo MD, Muralidharan P, Mackay CE, Evanson KW, Moreira-Junior L, Mata-Daboin A, Burris SK, et al. Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure.eLife. 2018; 7:e42628. doi: 10.7554/eLife.42628CrossrefMedlineGoogle Scholar5. Knot HJ, Nelson MT. Regulation of arterial diameter and wall [Ca2+] in cerebral arteries of rat by membrane potential and intravascular pressure.J Physiol. 1998; 508(pt 1):199–209. doi: 10.1111/j.1469-7793.1998.199br.xCrossrefMedlineGoogle Scholar6. Santana LF, Navedo MF. Molecular and biophysical mechanisms of Ca2+ sparklets in smooth muscle.J Mol Cell Cardiol. 2009; 47:436–444. doi: 10.1016/j.yjmcc.2009.07.008CrossrefMedlineGoogle Scholar7. Nelson MT, Cheng H, Rubart M, Santana LF, Bonev AD, Knot HJ, Lederer WJ. Relaxation of arterial smooth muscle by calcium sparks.Science. 1995; 270:633–637. doi: 10.1126/science.270.5236.633CrossrefMedlineGoogle Scholar8. Nieves-Cintron M, Flores-Tamez VA, Le T, Baudel MM, Navedo MF. Cellular and molecular effects of hyperglycemia on ion channels in vascular smooth muscle.Cell Mol Life Sci. 2021; 78:31–61. doi: 10.1007/s00018-020-03582-zCrossrefMedlineGoogle Scholar9. Tan Y, Ichikawa T, Li J, Si Q, Yang H, Chen X, Goldblatt CS, Meyer CJ, Li X, Cai L, et al. Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo.Diabetes. 2011; 60:625–633. doi: 10.2337/db10-1164CrossrefMedlineGoogle Scholar10. Lu T, Sun X, Li Y, Chai Q, Wang XL, Lee HC. Role of Nrf2 signaling in the regulation of vascular BK channel beta1 subunit expression and BK channel function in high-fat diet-induced diabetic mice.Diabetes. 2017; 66:2681–2690. doi: 10.2337/db17-0181CrossrefMedlineGoogle Scholar11. Nystoriak MA, Nieves-Cintron M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, et al. AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus.Circ Res. 2014; 114:607–615. doi: 10.1161/CIRCRESAHA.114.302168LinkGoogle Scholar12. Martin-Aragon Baudel M, Flores-Tamez VA, Hong J, Reddy GR, Maillard P, Burns AE, Man KNM, Sasse KC, Ward SM, Catterall WA, et al. Spatiotemporal control of vascular Ca(V)1.2 by alpha1(C) S1928 phosphorylation.Circ Res. 2022; 131:1018–1033. doi: 10.1161/CIRCRESAHA.122.321479LinkGoogle Scholar13. Nieves-Cintron M, Syed AU, Buonarati OR, Rigor RR, Nystoriak MA, Ghosh D, Sasse KC, Ward SM, Santana LF, Hell JW, et al. Impaired BK(Ca) channel function in native vascular smooth muscle from humans with type 2 diabetes.Sci Rep. 2017; 7:14058. doi: 10.1038/s41598-017-14565-9CrossrefMedlineGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesSorbs2 Deficiency and Vascular BK Channelopathy in DiabetesXiaojing Sun, et al. Circulation Research. 2024;134:858-871 March 29, 2024Vol 134, Issue 7 Advertisement Article InformationMetrics © 2024 American Heart Association, Inc.https://doi.org/10.1161/CIRCRESAHA.124.324241PMID: 38547252 Originally publishedMarch 28, 2024 KeywordsEditorialshyperglycemiamorbiditysrc homology domainsvasodilationPDF download Advertisement

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