医学
埃罗替尼
吉非替尼
肺癌
奥西默替尼
内科学
表皮生长因子受体
肿瘤科
皮疹
盐酸厄洛替尼
阿法替尼
表皮生长因子受体抑制剂
T790米
癌症
作者
Chinese Anti-Cancer Association Chinese Society of Lung Cancer
出处
期刊:PubMed
[National Institutes of Health]
日期:2019-02-20
卷期号:22 (2): 57-81
被引量:32
标识
DOI:10.3779/j.issn.1009-3419.2019.02.01
摘要
ErbB receptor tyrosine kinase inhibitors (EGFR-TKI), gefitinib, erlotinib, icotinib and aftinib, which are approved as a frontline treatment for patients with non-small cell lung cancer (NSCLC) who have tumors harboring EGFR mutations in China. And osimertinib was approved in second line setting for patients with EGFRT 790M-positive NSCLC. Rash, paronychia, diarrhea, stomatitis, liver dysfunction and (interstitial lung disease, ILD) are frequently observed in patients treated with EGFR-TKI. Chinese Society of Lung Cancer, Chinese Anti-Cancer Association, organized Chinese experts to develop the Chinese expert consensus on EGFR-TKI adverse event (AE) management based on domestic diagnosis and treatment of ADR and also incorporating international updated theory and recommendations. .
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