Diagnostic work-up of an incidental ultra-rare tumour, epithelioid haemangioendothelioma, in a Danish diagnostic centre

In this case report we present a woman in her late 40s with dual clinical presentation. First, the patient presented to general practice with muscular symptoms over months, including pain and a palpable mass in her right leg. Then acute cerebral symptoms appeared that required emergency hospitalisation. MRI scan of the head, chest X-ray, upper-body 18 F-FDG-PET/CT and CT scan were indicative of both a benign meningioma and malignant lung metastases. Subsequent diagnostic work-up at our diagnostic centre led to the final diagnosis; epithelioid haemangioendothelioma, with the primary site in the right leg and lung metastases, an ultra-rare type of cancer.