The liver is the most important organ in the body that plays a central role in the detoxification and excretion of many exogenous and endogenous compounds.Due to these functions, hepatic diseases continue to be among the main threats to public health, and that challenges health care professionals.Many liver diseases are chronic, meaning they last for years and may never go away.But even chronic liver diseases can usually be managed.The drugs that work on the liver are generally classified into two categories, one is antihepatotoxic agents, which generally antagonize the effects of any hepatotoxins causing any liver disease and another is hepatoprotective agents which prevent various types of liver infections prophylactically.Plants are the paramount source of herbal medicines.A plethora of data from the medicinal plants is available in literature.The present review is aimed at compiling data on promising herbs in concise manner, which are experimentally proved by the scientists as hepatoprotective. INTRODUCTION:The liver is a large glandular organ that plays an important role in maintaining vital functions such as maintenance, performance, and regulating the homeostasis of the body.The human liver comprising two main lobes; the right lobe is larger than the left.The liver involved in almost all biochemical pathways like carbohydrate, fat, protein, hormone and drug metabolism, production of bile and bile acid, synthesis of clotting factors and plasma protein, storage of minerals, vitamins and glycogen Fig. 1 1 .