医学
无容量
化疗
肿瘤科
肺癌
新辅助治疗
内科学
癌症
作者
Patrick M Forde,Jonathan Spicer,Shun Lu,Mariano Provencio,Tetsuya Mitsudomi,Mark M. Awad,Enriqueta Felip,Stephen R Broderick,Julie R. Brahmer,Scott J. Swanson,Keith Kerr,Changli Wang,Tudor-Eliade Ciuleanu,Gene B. Saylors,Fumihiro Tanaka,Hiroyuki Ito,Ke-Neng Chen,Moishe Liberman,Everett E. Vokes,Janis M. Taube
标识
DOI:10.1056/nejmoa2202170
摘要
In patients with resectable NSCLC, neoadjuvant nivolumab plus chemotherapy resulted in significantly longer event-free survival and a higher percentage of patients with a pathological complete response than chemotherapy alone. The addition of nivolumab to neoadjuvant chemotherapy did not increase the incidence of adverse events or impede the feasibility of surgery. (Funded by Bristol Myers Squibb; CheckMate 816 ClinicalTrials.gov number, NCT02998528.).
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