医学
骨关节炎
物理疗法
临床试验
疾病严重程度
髋关节手术
药物试验
内科学
外科
关节置换术
替代医学
病理
出处
期刊:PubMed
日期:1997-04-01
卷期号:24 (4): 779-81
被引量:358
摘要
The severity or algofunctional indices for hip and knee osteoarthritis (OA) have been used in Europe for about 10 years. They were validated, then published between 1982 and 1987. They are useful mainly as outcome measures in OA trials, and also for appraising the severity of patient function: a score above 11-12 points after appropriate treatment indicates surgery. Most patients recruited in OA trials have a score of 9-11 (SD 2.3 to 3.8), decreasing about 30 to 40% with the active drug. The effect size reaches 1.3 to 1.8. The indices have 2 advantages: they are structured separately for hip and for knee OA and the same instrument serves as a measure of severity (disability scale) and as an outcome measurement tool in trials.
科研通智能强力驱动
Strongly Powered by AbleSci AI