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Analysis of trends and driving factors in burden of Alzheimer's disease and other dementias from 1990 to 2021 and projections for 2050: A comprehensive perspective based on GBD 2021 相关领域
疾病负担
疾病负担
人口学
环境卫生
医学
疾病
人口
大流行
流行病学
老年学
人口老龄化
全球人口
透视图(图形)
毒物控制
伤害预防
全球卫生
趋势分析
地理
边疆
索引(排版)
质量调整寿命年
多元分析
人为因素与人体工程学
自杀预防
2019年冠状病毒病(COVID-19)
人口增长
中国
梅德林
共病
公共卫生
人口健康
职业安全与健康
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Abstract BackgroundThe disparities in Alzheimer's disease and other dementias (ADOD) burden across global regions have been further exacerbated following the COVID-19 pandemic, necessitating urgent systematic research into its changing trends and driving factors.ObjectiveTo evaluate trends and driving factors of ADOD burden over the past 32 years and analyze changes during the COVID-19 pandemic.MethodsData were extracted from the Global Burden of Disease 2021. We used the average annual percentage change to assess ADOD burden trends from 1990 to 2021, and quantified the drivers of burden through decomposition analysis. We further utilized frontier analysis to explore the relationship between socio-demographic index (SDI) and disability-adjusted life-years (DALYs), and employed the Bayesian age-period-cohort (BAPC) model to project DALYs trends for ADOD from 2022 to 2050.ResultsFrom 1990 to 2021, global age-standardized rates (ASRs) of prevalence, incidence, years live |
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(2025-6-4)