| 标题 |
[高分]
 Agar Plate–Based Method for the Selection of Antibiotic-Resistant Bacterial Strains 琼脂平板法筛选耐药菌株
相关领域
抗生素
微生物学
抗生素耐药性
金黄色葡萄球菌
选择（遗传算法）
细菌
琼脂
生物
抗菌剂
抗药性
琼脂平板
抗菌药物
遗传学
计算机科学
人工智能
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| 网址 | |
| DOI | |
| 其它 |
Abstract Identifying the molecular mechanisms underlying antibiotic resistance is important, as it can reveal key information on the mode of action of a drug and provide insights for the development of novel or improved antimicrobials. Here, we describe an agar-based method for the selection of bacterial strains with increased antibiotic resistance, and how the increase in resistance can be confirmed by a spot-plating assay. As a specific example, we describe the selection of Staphylococcus aureus strains with increased resistance to oxacillin; however, the protocol can be easily adapted and used with other bacteria and antibiotics. |
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