医学
放射外科
相伴的
放射治疗
乳腺癌
脑转移
癌症
全身疗法
肿瘤科
美金刚
转移
内科学
疾病
痴呆
作者
Dario Trapani,Ayal A. Aizer,Nancy U. Lin
标识
DOI:10.1016/j.hoc.2022.08.017
摘要
The management of patients with breast cancer and brain metastases (BMs) is exquisitely multidisciplinary. Patients presenting with a symptomatic BM may be offered neurosurgical resection, followed by radiation. Stereotactic radiosurgery (SRS) is preferred over whole-brain radiotherapy (WBRT) in most patients presenting with a limited number of BMs, whereas WBRT with hippocampal-sparing and concomitant memantine is preferred for patients with multiple BMs. There is a growing role for systemic therapy, in some cases in lieu of local therapy, particularly in patients with HER2+ breast cancer.
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