[Noninvasive assessment of age-related changes in female skin microrelief].

Age-related changes in female skin microrelief (33 nonsmoking women at the age from 17 to 80 years) were analyzed by the use of VISIOSCAN VS 98. Measurements were taken on inner side of left forearm at the distance of 2 cm away from the bend of the elbow. It was demonstrated that most responsive indicators of skin chronological aging in magnitudes of correlation coefficient (R) and time increment (I) of age-related changes are the following skin microrelief parameters: V(relievo), R = 0.45, I(V) = 1.06; Ser (roughness), R = 0.58, I(Ser) = 1.13; Sew(wrinkles), R = 0.48, I(Sew) = 1.03. Based on microrelief parameters, the combined equation of morph functional skin age (T) has been derived by the multiple linear regression: T = -61.66 + 0.15 V + 20.05 Ser + 1.67 Sew. The multiple regression coefficient is equal to 0.72.