CD28
细胞毒性T细胞
CD8型
生物
细胞生物学
效应器
免疫学
免疫系统
癌症研究
生物化学
体外
作者
Étienne Humblin,Isabel Korpas,Jiahua Lu,Dan Filipescu,Verena van der Heide,Simon Goldstein,Abishek Vaidya,Alessandra Soares‐Schanoski,Beatrice Casati,Myvizhi Esai Selvan,Zeynep H. Gümüş,Andreas Wieland,Mauro Corrado,Leona Cohen‐Gould,Emily Bernstein,Dirk Homann,Jerry E. Chipuk,Alice O. Kamphorst
出处
期刊：Science immunology
[American Association for the Advancement of Science]
日期：2023-08-04
卷期号：8 (86)
被引量：23
标识
DOI：10.1126/sciimmunol.adg0878
摘要
During persistent antigen stimulation, such as in chronic infections and cancer, CD8 T cells differentiate into a hypofunctional programmed death protein 1-positive (PD-1
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