Magnetic P(St-MA) Microspheres：Preparation, Characterization and Interaction with BSA

Taken the nanoparticles Fe3O4 as the magnetic carrier, and styrene ( St ) and Methyl Acrylate (MA) as the monomers, the magnetic polystyrene-methyl acrylate (P(St-MA)) microspheres were prepared by microsuspension copolymerization. The effect of various parameters(e.g. reaction temperature, initiator, Fe3O4/styrene ratio and disperser) on the properties of the P(St-MA) microspheres were studied.The microspheres were characterized by different techniques (e.g. SEM, VSM, TG-DSC, FTIR, ). The interaction of magnetic microspheres and BSA were studied by microcalorimetry. The results showed the P(St-MA) microspheres, with abundant –COOH, superparamagnetic and high magnetic content, were possessed much higher protein adsorbance compared to those of magnetic polystyrene(PS) microspheres.