Combined Enzyme and Transition‐Metal Catalysis for Dynamic Kinetic Resolutions

Abstract The preparation of optically pure alcohols, axially chiral allenes, and amine derivatives by using enzymes and transition‐metal catalysts through dynamic kinetic resolution (DKR) is reviewed. After a general introduction into enzymatic kinetic resolutions and racemizations catalyzed by transition‐metal complexes, selected examples of DKRs are presented, from early work to more recent outstanding contributions, and also applications of this approach.