精液
精液质量
萧条(经济学)
精子
逻辑回归
医学
混淆
精子活力
精液分析
置信区间
内科学
生物
男科
怀孕
不育
经济
宏观经济学
遗传学
作者
Yongfeng Wang,Yuan Zhang,Yunyi Yang,Lihui Tu,Jigao Yang,Zhou Zhang,Tianqing Meng,Xianglong Jiang,Wen-Bing Zhu,Yu-Shan Li,Huiping Zhang,Kai Zhao,Xinzong Zhang,Chunyan Liu
出处
期刊:Research Square - Research Square
日期:2021-07-13
标识
DOI:10.21203/rs.3.rs-653536/v1
摘要
Abstract Background: Depression is a potential factor affecting semen quality. However, the relationship between depression and semen quality remains to be fully elucidated. We investigated the association between depression and semen quality in men during the COVID-19 pandemic. Methods: Cross‐sectional, participants completed a questionnaire assessing lifestyle factors the Patient Health Questionnaire-9 (PHQ-9) was used to evaluate the psychological depression status of subjects. Semen quality assessment implements the requirements of the fifth edition of the World Health Organization (WHO )manual ,multivariable logistic regression analysis and linear regression analysis were conducted to assess the associations between depression and semen quality. Results: Of the 896 participants, 173 were depressed (19.30%). A Linear regression model was fitted to assess the strength and significant level of the association between depressive symptoms and semen quality. After adjusting for potential confounders, depression was significantly associated with 9.27 (95% confidence interval [CI] 3.39, 15.15), 0.57(95% CI 0.27, 0.87), 62.20 (95% CI 32.93, 91.48), and 12.96 (95% CI 10.55, 15.37) reduction in sperm concentration, sperm volume, total sperm count, and progressive motility, respectively. Which are consistent with the logistic regression analysis results. The semen concentration and total sperm count were linearly correlated with depression scores, whereas the semen volume and progressive motility of sperm were nonlinearly correlated with depression scores. Conclusions: Depression were associated with lower levels of semen concentration, semen volume, total sperm count, and progressive motility, which could affect male reproductive health.
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