Phthalide Derivatives from Meum athamanticum Jacq

Abstract A detailed investigation of non polar extracts of Meum athamanticum Jacq. rhizome (Um- belliferae) has led to the isolation of three phthalide derivatives. Sedanenolide, 6.6′,7.3′a-dili- gustilide and ligustilidiol have been identified by their spectral data. Furthermore, occurrence of such compounds seems to suggest assignment of intermediate biogenetic part to (Z)-ligustilide, the most accumulated phthalide in umbelliferous plants.