Effect of continuous intravenous infusion of lidocaine on emergence agitation after sevoflurane inhaled anesthesia in children

Objective To observe the effect of continuous intravenous infusion of lidocaine on emergence agitation after sevoflurane inhaled anesthesia in children.Methods Sixty children selected for adenotonsillectomy were randomly divided into 2 groups(n=30):group L and group S.In group L,1.5 mg·kg-1 lidocaine was injected before tracheal intubation,then 2 mg·kg-1·h-1 IV intraoperatively.In group S,the same volume of saline was given.In 2 groups,anesthesia were maintained with inhaled sevoflurane.The MAP and HR before induction(T0)and during extubation(T1),operation time,extubation time and time spent in PACU were recorded.After extubation,the pediatric anesthesia emergence delirium(PAED) scale was evaluated.Results There were no significant differences in time of extubation and time spent in PACU.Compared to group S,the MAP and HR were significantly decreased during extubation in group L(P0.05).The PAED scores and incidence of EA were lower in group L than those in group S(P0.05).Conclusion Continuous intravenous infusion of lidocaine can reduce the cardiovascular reaction due to extubation and the incidence of EA after sevoflurane anesthesia in children.