The influence of casein hydrolysate treated by papain on growth of lactic acid bacteria(Lactobacillus bulgaricus:Streptococcus thermophilus = 1:1) was studied.The hydrolysate treated by papain for 8 h displayed the highest growth-promoting activity for the strains.In addition,the effect of casein hydrolysate on the bacterial viability,the yield of lactic acid and exopolysaccharide from lactic acid bacteria was determined.These results suggested that the yield of lactic acid and exopolysaccharide could be improved by 33.1% and 30.4%,respectively.