Early Hematoma Enlargement in Primary Intracerebral Hemorrhage

Background: Early hematoma growth is not uncommon in patients with intracerebral hemorrhage. It is a devastating complication that independently predicts poor outcome. The early hematoma enlargement is usually defined as an absolute increase in hematoma volume of greater than 33% on repeat CT scan. To date, no ideal animal model can mimic the exact pathophysiological process of early hematoma growth. Keywords: Primary cerebral hemorrhage, hematoma enlargement, mechanisms, predictors.