化学
重氮甲烷
卤化物
卤化氢
溶剂
催化作用
有机化学
组合化学
卤素
烷基
作者
Marjan Jereb,Janja Lakner
出处
期刊:Tetrahedron
[Elsevier]
日期:2016-09-01
卷期号:72 (37): 5713-5723
被引量:7
标识
DOI:10.1016/j.tet.2016.08.003
摘要
A broad set of structurally different carboxylic acids were transformed into their trimethylsilyl esters with HMDS in a practically completely solvent-free process, while a catalytic amount of iodine was required in some cases. The process has several advantages over the known methods: untreated reactants, air atmosphere, mild and neutral conditions, no evolution of hydrogen halide, no need of an additional base, low amount of waste, completely without chromatography, low consumption of energy, and operational simplicity.
科研通智能强力驱动
Strongly Powered by AbleSci AI