CASE OF THE TRANSFORMATION OF PSORIASIS INTO CUTANEOUS T-CELL LYMPHOMA

银屑病 皮肤病科 医学 淋巴瘤 入射(几何) 恶性转化 癌症 恶性淋巴瘤 病理 内科学 物理 光学
作者
V.Yе. Tkach,О.Д. Александрук,Ivan Kostyshyn,M.S. Voloshynovych,Galyna Girnyk,S.M. Romanchuk
出处
期刊:Experimental Oncology [LLC MORION]
卷期号:46 (1): 68-71 被引量:1
标识
DOI:10.15407/exp-oncology.2024.01.068
摘要

Psoriasis is a long-known skin pathology, the incidence of which is constantly rising, though it is not possible to clearly establish the trend due to the differences in the research design. In recent years, the number of cases among children and adolescents has increased. Psoriasis becomes more aggressive, severe forms are more common. It can be combined with other diseases but is rarely complicated. Isolated cases of the transformation of psoriatic plaques into skin cancer have already been described in the literature. Probable causes were the long-term use of photosensitizers and phototherapy, naphthalene, and tar. However, in general, the risk of the malignant recurrence in patients with psoriasis does not increase significantly. We present a clinical observation of the transformation of psoriasis into cutaneous T-cell lymphoma in a patient with more than 37 years of psoriasis experience, where on the background of typical psoriatic rashes, fungal growths of doughy consistency appeared, which were initially misinterpreted as a warty form of psoriasis. Based on the data of additional methods of examination and the results of histological examination, the diagnosis was clarified. Specific treatment was prescribed, which proved its effectiveness. The probable causes of degeneration, in our opinion, are prolonged irritating external therapy and excessive insolation.
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