整体
分路器
栏(排版)
范迪姆特方程
流量(数学)
色谱法
化学
灵敏度(控制系统)
洗脱
压力降
分析化学(期刊)
材料科学
机械
高效液相色谱法
计算机科学
数学
工程类
几何学
电信
物理
电子工程
催化作用
帧(网络)
生物化学
标识
DOI:10.1002/jssc.202200755
摘要
In this study an adaptable end-column platform was fitted to a commercially available monolith, which enabled the column to be fitted with a flow splitting device. A variety of flow splitting adapters could be incorporated into the platform, and in this study a radial flow stream splitter was utilised. The advantage of the radial flow stream spitter was that it overcame issues relating bed density variations that could cause bands to distort in the radial cross section of the column. Using propylbenzene as a test standard in isocratic elution mode, height equivalent to a theoretical plate (HETP) curves were constructed across ten flow rates, and it was found that the column efficiency improved by as much as 73%. Furthermore, the dual outlet flow splitter enabled a very substantial reduction in column back pressure, with the decrease being consistently between 20 to 30% depending on the column length. Additionally, sensitivity increased by 45%, consistent with the observed increase in efficiency. The adaptable end-column platform could be retro fitted to almost any commercial column with the expectation of gaining efficiency, sensitivity and reducing back pressure. This article is protected by copyright. All rights reserved
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