Research progress on immune response of macrophage and Mycobacterium tuberculosis

Macrophage is the main host cell of Mycobacterium tuberculosis in the body. Cellmediated immune response is the main immune protection mechanism in the anti-Mycobacterium tuberculosis. Macrophage kills Mycobacterium tuberculosis through phagocytosis, lysosome fusion,presenting antigens of Mycobacterium tuberculosis, producing a variety of cytokines, reactive oxygen intermediates and reactive nitrogen intermediates, apoptosis and many other ways. Meanwhile,Mycobacterium tuberculosis can take a variety of ways to escape the immune function of macrophages.This article reviews the research progress on immune response of macrophage and Mycobacterium tuberculosis. Key words: Macrophage;  Mycobacterium tuberculosis; Immune response