凝聚
芦丁
喷雾干燥
壳聚糖
粒径
化学工程
生物利用度
化学
傅里叶变换红外光谱
材料科学
色谱法
有机化学
抗氧化剂
生物信息学
生物
工程类
作者
Fideline Tchuenbou-Magaia,Roberta Tolve,Uchechukwu Anyadike,Marco Giarola,Fabio Favati
标识
DOI:10.1007/s11694-022-01340-2
摘要
Abstract There is a growing interest in co-encapsulating multiple species to harness potential synergy between them, enhance their stability and efficacy in various products. The aim of this work was to co-encapsulate vitamin D 3 and rutin inside chitosan-zein microparticles using a simple and easily scalable process for food fortification. This was achieved via anti-solvent precipitation coupled with spray-drying. Free-flowing powders of spherical microparticles with wrinkled surface and particle size < 10 μm were obtained. The encapsulation efficiency was 75% for vitamin D 3 and 44% for rutin and this could be attributed to their different molecular size and affinity to the aqueous phase. The physicochemical properties were characterized by X-Ray powder diffraction and Fourier transform infrared spectroscopy. The two crystalline bioactive compounds were present in the microparticles in amorphous form, which would allow for better bioavailability when compared to non-encapsulated crystalline solid. Therefore, the obtained microparticles would be suitable for use as food ingredient for vitamin D 3 fortification, with the co-encapsulated rutin acting as stability and activity enhancer.
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