[Objective]To study the loss-control fertilizer' s efficiency and economic efficiency of the winter wheat.[Method]Field experiments of wheat applying with different fertilizer were carried out.[Result]When compared to the production of wheat in general compound fertilizer area,the production of wheat increased by 2.5%in the equivalent nutrient loss-control fertilizer area,and it was equal to the reduced dosage 16%loss-control fertilizer' s area;the growth and development of wheat in the latter part of he loss-control fertilizer district was outstanding, with adequate fertility;the twice using of N fertilizer averagely as basic and supplement could increase fertilizer efficiency and production of 7.7%compared to using as whole basic.Cost-effectiveness analysis of different fertilizer showed that input - output ratio of the loss-control fertilizer was higher than ordinary fertilizer,the economic benefits of the reduced dosage of loss-control fertilizer were more obvious,its net income increased by 315.0 yuan/hm~2.[Conclusion]Loss-control fertilizer had a significant effect of loss-control and worth to be applied and extended in large area.