Objective The discussion Perindopril and amlodipine besylate union treatment primary hypertension curative effect.Methods Divides into the treatment group and the control group stochastically 80 example primary patients with elevated blood pressure,the control group 40 examples uses Perindopril,the treatment group 40 examples Perindopril's foundation in the application to add with the amlodipine besylate,observes two groups of medicines to hypertension curative effect.Results Treatment group total effectiveness 90%,control group total effectiveness 77.5%,two groups of differences remarkable(P0.05).Conclusion Perindopril and amlodipine besylate treat hypertension curative effect affirmation jointly,responds not good few,is worth promoting.