Pioglitazone vs. Rosiglitazone in Older Patients with Type 2 Diabetes

Two thiazolidinediones are available in the U.S.: pioglitazone (Actos) and rosiglitazone (Avandia). However, researchers have raised concerns about the cardiovascular safety of these drugs. In this retrospective cohort study, Canadian investigators assessed risk for myocardial infarction, heart failure, and death in nearly 40,000 older patients …