The relationship between the expression of HBsAg and HBcAg in the liver tissue and the content of HBV-DNA in serum of patients with chronic hepatitis B

Objective To discuss the relationship between the expression of HBsAg and HBcAg in the liver tissue and the content of HBV-DNA in serum of patients with chronic hepatitis B. Methods 51 patients with chronic hepatitis B were choose randomly and detected by the content of HBV-DNA,and the expression of HBsAg and HBcAg in liver tissue of the patients.Results There were positive correlation between the expressive intensity of HBcAg in liver tissue and the content of HBV-DNA in serum,the correlation between the expressive intensity of HBsAg in liver tissue and HBV-DNA in serum is feeblish. Conclusion It is more reliable to take the expressive degree of HBsAg and HBcAg in liver tissue combining the content of HBV-DNA in serum as antivirus therapeutical indexes than single one.