Analysis on 5277 cases of adverse drug reactions of traditional Chinese medicine

AIM To analyze adverse drug reactions(ADRs) of traditional Chinese medicine(TCM).METHODS Using EXCEL and SPSS sofewares we analyzed 5 277 ADR cases from Shanghai Center for Adverse Drug Reactions Monitoring during the period from 2006 to 2008.Furthermore,we calculated proportional reporting ratios(PRRs) for every kind of drug and ADRs.RESULTS ADRs of TCM mainly included skin appendix damage,allergic reaction and gastrointestinal hurt.The rate of serious ADRs was 2.8%.The method of PRRs identified 91 signals which were required further evaluation.CONCLUSION Most ADRs of TCM are mild,while significant ADRs are less.The value of PPRs is conveniently calculated for monitoring the signal of ADRs.