Charting the path for l -tyrosine derivatives: from engineering strategies to microbial cell factories

-coumaric acid, and L-3,4-dihydroxyphenylalanine (L-DOPA) as the key nodes, it highlights the cutting-edge advances primarily within the last five years. Finally, the review critically assesses the persistent challenges and future opportunities, offering a strategic roadmap to accelerate the biomanufacturing of L-Tyr-derived natural products.