毛细管电色谱
化学
毛细管作用
共价键
共价有机骨架
色谱法
选择性
多孔性
相(物质)
毛细管电泳
分析化学(期刊)
化学工程
有机化学
材料科学
工程类
复合材料
催化作用
作者
Deying Kong,Zilin Chen
标识
DOI:10.1002/elps.201800235
摘要
Abstract Because of unique properties like permanent porosity, low density and large surface area, covalent organic frameworks are attractive microporous materials as stationary phase for CEC. Among them, COF‐TpPa‐1 possesses extraordinary chemical stability and common features of covalent organic frameworks. So, COF‐TpPa‐1 could be a promising material as stationary phase to enhance separation selectivity and tolerate the acid or alkaline electrochromatographic separation conditions. Here, we report the preparation of COF‐TpPa‐1 modified capillary column by in situ growth for electrochromatographic separation. The immobilization of COF‐TpPa‐1 on the inner wall of capillary column was confirmed by Fourier transform infrared spectroscopy, scanning electron microscopy and X‐ray diffraction. The fabricated COF‐TpPa‐1 modified capillary column indicated good resolution for the separation of neutral analytes, nonsteroidal anti‐inflammatory drugs and food additives in open‐tubular CEC mode. Compared with bare capillary column, the COF‐TpPa‐1 modified capillary column improved separation selectivity remarkably for tested analytes, including hydrophobic, π–π and hydrogen bond interactions. Besides, the prepared capillary column showed excellent repeatability and stability. The intraday, interday and column‐to‐column relative standard deviations of migration time for neutral analytes were less than 3.54%. This work shows enamine‐linked covalent organic frameworks have great potential as stationary phases in CEC.
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