材料科学
聚电解质
壳聚糖
纳米技术
执行机构
纳米孔
制作
化学工程
海藻酸钠
人工肌肉
自愈水凝胶
药物输送
聚合物
钠
复合材料
高分子化学
计算机科学
病理
人工智能
工程类
冶金
医学
替代医学
作者
Hongyang Cui,Na Pan,Wenxin Fan,Chun-Zhao Liu,Yanhui Li,Yanzhi Xia,Kunyan Sui
标识
DOI:10.1002/adfm.201807692
摘要
Abstract The design of smart hydrogel actuators fully constructed from natural polymers for assessing the biomedical applications is important but challenging. Herein, an extremely simple, green, and ultrafast strategy is presented for preparing robust gradient all‐polysaccharide polyelectrolyte complex hydrogel actuators. Driven by diffusing of low molecular weight chitosan into high molecular weight sodium alginate solution, a nanoporous, ultrastrong, and gradient chitosan/sodium alginate complex hydrogel film with adjustable thickness can be directly generated on the interface of two solutions within minutes. The as‐prepared film can provide superfast temperature, ionic strength, and pH‐triggered programmable deformations, and perform a distinct sequential double folding behavior due to the competitive effect between complexed and noncomplexed segments of polyelectrolyte. Besides, patterning Ca 2+ to locally crosslink sodium alginate in the film enables various more complex shape transformations. This green and simple diffusion‐driven strategy provides significant guidance for fabricating bio‐friendly actuators with applications in drug delivery, tissue engineering, soft robotics, and active implants.
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