生物
初级
DNA钳
DNA聚合酶Ⅱ
复制蛋白A
染色体复制控制
DNA聚合酶
DNA复制
凝聚体
单链结合蛋白
真核细胞DNA复制
分子生物学
DNA聚合酶δ
DNA
遗传学
DNA结合蛋白
基因
基因组
核糖核酸
逆转录酶
转录因子
出处
期刊:Cold Spring Harbor Perspectives in Biology
[Cold Spring Harbor Laboratory]
日期:2013-09-01
卷期号:5 (9): a010199-a010199
被引量:138
标识
DOI:10.1101/cshperspect.a010199
摘要
Poxviruses are large, enveloped viruses that replicate in the cytoplasm and encode proteins for DNA replication and gene expression. Hairpin ends link the two strands of the linear, double-stranded DNA genome. Viral proteins involved in DNA synthesis include a 117-kDa polymerase, a helicase-primase, a uracil DNA glycosylase, a processivity factor, a single-stranded DNA-binding protein, a protein kinase, and a DNA ligase. A viral FEN1 family protein participates in double-strand break repair. The DNA is replicated as long concatemers that are resolved by a viral Holliday junction endonuclease.
科研通智能强力驱动
Strongly Powered by AbleSci AI