Polymer concrete (PC) with suitable mechanical and chemical properties was prepared. The propertiesof PCs are dependent upon the type of resins and filler materials. This research paper presents an assessmentof the chemical resistance of polymer concretes in various chemical compositions. Epoxy resin was used tofabricate PC samples. The sample blocks were exposed to hostile environment in strong acidic and alkaliconditions. The loss of compressive strength of the samples exposed to corrosive environment wasinsignificant. The strength of corrosive environment had significant effect on the chemical resistance of thefabricated PC samples. A desired blend of the optimized chemical composition of epoxy was used and testedin all corrosive environments. These samples were successfully passed all the designed testing conditions.