The influence factors of starch grafting acrylonitrile on the grafting ratio and the grafting efficiency were researched and obtained the optimum process conditions as follows:the mass proportion of dissoluble starch to acrylonitrile is 1∶3,the concentration of ceric ammonium nitrate is 6 mg/L,grafting temperature is 35 ℃,grafting time is 2 h,under the condition,the grafting rate and grafting efficiency are 172%,92% respectively.The polymer flocculating agent prepared is better than inorganic one in the aspects of turbidity,COD removal ratio and deposition speed.