Damaged hair retrieval with ceramide-rich liposomes.

角质层 脂质体 化学 生物物理学 胆固醇 神经酰胺 角细胞 膜 生物化学 脂质双层 生物 遗传学 细胞凋亡
作者
Sandra Méndez,A. M. Manich,Meritxell Martı́,José Luís Parra,Luísa Coderch
出处
期刊:PubMed [National Institutes of Health]
卷期号:62 (6): 565-77 被引量:3
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摘要

Lipids from human hair consist mainly of cholesterol esters, free fatty acids, cholesterol, ceramides, and cholesterol sulfate. They are structured as lipid bilayers in the cell membrane complex (CMC) and make a large contribution to diffusion, cell cohesion, and mechanical strength. The loss of these lipids could impair the integrity of the hair, leading to deterioration in its tensile properties. Internal wool lipids (IWL) resemble those of the membranes of other keratinic tissues such as human hair or stratum corneum. The application of IWL structured as liposomes on pretreated hair samples has been demonstrated to restore the natural properties of the fibers. This study seeks to apply IWL liposomes to untreated hair fibers and to hair fibers subjected to chemical treatment. Differences in the lipidic composition of all chemically treated hairs were found with respect to the untreated ones. Lipid recovery of damaged hair due to the application of IWL liposomes was corroborated by lipid analysis of the hair. A high resistance to break of hair samples post-treated with IWL liposomes was observed. An increase in hydrogen bonds and electrostatic forces and an improvement in the cohesion between matrix and filaments were detected, probably because of some lipid recovery.

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