细胞周期
背景(考古学)
代谢途径
生物
癌细胞
细胞生长
癌症
代谢控制分析
细胞
脂质代谢
细胞生物学
新陈代谢
细胞周期进展
细胞代谢
生物信息学
胰岛素
生物化学
生物技术
遗传学
古生物学
作者
Lucía C. Leal-Esteban,Lluís Fajas
标识
DOI:10.1016/j.bbadis.2020.165715
摘要
Cancer proliferation and progression involves altered metabolic pathways as a result of continuous demand for energy and nutrients. In the last years, cell cycle regulators have been involved in the control of metabolic processes, such as glucose and insulin pathways and lipid synthesis, in addition to their canonical function controlling cell cycle progression. Here we describe recent data demonstrating the role of cell cycle regulators in the metabolic control especially in studies performed in cancer models. Moreover, we discuss the importance of these findings in the context of current cancer therapies to provide an overview of the relevance of targeting metabolism using inhibitors of the cell cycle regulation.
科研通智能强力驱动
Strongly Powered by AbleSci AI