脑啡肽酶
肾素-血管紧张素系统
肾脏疾病
医学
内科学
血管紧张素II
内分泌学
疾病
心脏病学
药理学
生物
血压
酶
生物化学
出处
期刊:Wiadomości lekarskie (Warsaw Poland)
[ALUNA]
日期:2019-01-01
标识
DOI:10.36740/wlek201911207
摘要
Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and high cardiovascular mortality. Data from other populations and animal experiments suggests that angiotensin-neprilysin inhibition may be superior to renin-angiotensin-aldosterone system inhibition in reducing the risk of cardiovascular mortality and retarding the progression of CKD. The review summarizes the existing evidence on the potential benefits of angiotensin-neprilysin inhibitor (ARNi) in CKD.
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