骨整合
材料科学
骨愈合
氧化应激
合金
再生(生物学)
抗氧化剂
生物医学工程
糖尿病
牙科
植入
冶金
医学
化学
外科
内科学
内分泌学
生物化学
细胞生物学
生物
作者
Jiahui Rao,Yujin Li,Jiwei Sun,Hairui Gao,Chen Yang,Yongqing Ma,Ranbo Yu,Xueqing Zheng,Yumei Ding
摘要
. Beyond biological advantages, the alloying of Li and Sr endowed the Zn alloy with significantly improved tensile strength for mechanical support with up to 6 times the UTS and 8 times the YS of pure Zn, and a uniform degradation mode to prevent localized rupture. Overall, Zn-Li-Sr alloy implants demonstrate promising applications for bone regeneration under diabetic conditions, their multifunctional properties not only address the physiological challenges posed by diabetes but also provide robust mechanical support and controlled degradation. This study provides valuable insights into the design and potential clinical applications of implants for bone regeneration under diabetic conditions.
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