Domino reactions of 1-(2-alkoxyaryl)-3-akylprop-2-yn-1-ones with sodium sulfide leading to thiochromen-4-one derivatives

A simple and practical approach to thiochromen-4-one derivatives has been developed through domino reactions of 1-(2-alkoxyaryl)-3-akylprop-2-yn-1-ones and sodium sulfide nonahydrate. The domino reactions underwent sequential addition and cyclization via cleavage of aromatic C–O bonds.