Diagnosis and management of pancreatic tumor in children ( 15 cases of report)

Objective To summarize the clinical characteristics of diagnosis and management of pancreatic tumor children.Methods Between January 2002 and 2010 January,total 15 patients suffering from pancreatic tumor underwent treatment in our centre.Their clinical data were retrospectively summarized and analyzed in this study.The mean age of all patients (male 8,female 7) was 11.3 years old (ranging from 45 d to 17 y).Clinical manifestations of them were listed as follows:9 of all have symptoms of abdominal pain,among them,2 children were associated with jaundice.Abdominal mass were found in 6 patients.The result of supersonic examination and CT scanning indicated a pancreatic occupation in all patients.In term of surgical procedures,6 patients underwent laparoscopic pancreatic body resections and local reactions using traditional open approach were taken in 4 patients,distal pancreatectomy was done in 4 patients and pancreatoduodenectomy was performed in 1 patients.Results No mortality was found in this study.The postoperative pathological results revealed pancreatic solid pseudopapillary tumor in 8 cases,pancreatoblastoma in 4 cases,1 pancreatic angioma and 1 non function islet tumor,as well as pancreatic cancer in 1 case.The fellow-up period ranged from 1 to 8 years,and all population survived.No recurrence and metastasis was found in 14 cases.The patient with pancreatic cancer was found a hepatic metastasis in second years after surgery,and underwent metastatic tumor resection.Conclusions Children pancreatic tumor is relatively rare in clinics.Solid pseudopapillary tumor and pancreatoblastoma are the commonest pathological type.The better curative efficacy will be taken for both laparoscopic and open approach radical resection.However,post-operative pancreatic cancer was liable to recur and metastasize,and long-term of fellow-up is still needed to evaluate the life quality in patients. Key words: Pancreatic neoplasms;  Digestive system surgical procedures;  Neoadjuvant therapy