Liver alveolar hydatid blood flow: imaging features on dual-source dual-energy CT and pathologic findings

Objective To explore the value of the dual-source dual-energy CT iodine imaging on blood flow characteristics of liver hydatid(HAE).Methods A retrospective analysis of pre-operative dualsource dual-energy CT including a conventional abdominal scan and 3 phasic scans was performed in 18 patients with surgically and pathologically proven HAE(n=18).The iodine values in different scanning(arterial phase,portal venous phase and parenchymal phase) and different organizational structures(hydatid tissues,normal liver tissues,edge tissue of the lesion and normal liver) were recorded.Pathological examination and micro-vessel density(MVD) count were performed in these different tissues.The iodine results of different phases and different tissues were compared with Rank test.The correlation of iodine value and MVD were performed with Spearman method.Results MVD median of hydatid tissues,regional tissues,edge tissue of the lesion and normal liver were 0.00,25.00 and 4.00/HPF respectively.The median iodine value of hydatid tissues in arterial phase,portal venous phase and parenchymal phase were 0.300,0.150 and 0.150 mg/ml(Z=l.216,P＞0.05) respectively.The median iodine value of edge tissue of the lesion and normal liver in 3 phases were 0.350,2.150 and 2.550 mg/ ml respectively.The median iodine values of normal liver tissues in 3 phases were 0.100,1.600 and 1.900 mg / ml(Z values were 28.800 and 31.886,P＜0.01) respectively.In the same phase of arterial phase,portal venous phase and parenchymal phase,the iodine values showed statistically significant difference(P＜0.05).The iodine values of edge tissue of the lesion and normal liver in 3 phases showed significant difference between the arterial phase and portal venous phase(P＜0.017).The portal venous phase