Clinical investigation of domestic clopidogrel in patients of coronary artery disease with diabetes mellitus.

Objective To evaluate the safety and efficacy of domestic clopidogrel(Talcom) in patients with coronary artery disease and diabetes mellitus.Methods 168 patients who hospitalized for coronary artery disease and successfully received coronary stenting were divided into Talcom group(n=73) and Plavix(imported clopidogrel as control) group(n=95).The incidence of major adverse cardiac events(MACE) and bleeding between the two groups were compared in 6 months follow-up after operation.Results There were no significant difference about the incidence of MACE and bleeding between the two groups after 6 months follow-up.Conclusion The efficacy and safety of domestic clopidogrel(Talcom) is similar to that of imported clopidogrel(Plavix).