Torque‐Driven Orientation Motion of Chemotactic Colloidal Motors

Abstract We report a direct experimental observation of the torque‐driven active reorientation of glucose‐fueled flasklike colloidal motors to a glucose gradient exhibiting a positive chemotaxis. These streamlined flasklike colloidal motors are prepared by combining a hydrothermal synthesis and a vacuum infusion and can be propelled by an enzymatic cascade reaction in the glucose fuel. Their flasklike architecture can be used to recognize their moving posture, and thus the dynamic glucose‐gradient‐induced alignment and orientation‐dependent motility during positive chemotaxis can be examined experimentally. The chemotactic mechanism is that the enzymatic reactions inside lead to the glucose acid gradient and the glucose gradient which generate two phoretic torques at the bottom and the opening respectively, and thus continuously steer it to the glucose gradient. Such glucose‐fueled flasklike colloidal motors resembling the chemotactic capability of living organisms hold considerable potential for engineering active delivery vehicles in response to specific chemical signals.