促炎细胞因子
巨噬细胞
黄瘤
泡沫电池
病理
医学
炎症
免疫学
生物
体外
生物化学
作者
Yan Huang,Haiqiang Dou,Baiping Cui,Yun Bai,Juan Wang,Qian Du,Yongxian Lai,Yeqiang Liu,Xiaolei Ding
摘要
The accumulation of dermal foam cells, the lipid-laden macrophages is the primary histopathological feature of eruptive xanthomas. Yet, the activation and implications of the foamy macrophages in eruptive xanthomas remain unknown. We investigated foamy macrophage activation and found that these cells are proinflammatory. More interestingly, foam cells in eruptive xanthomas express TREM2, a recently identified marker for lipid-laden macrophages in atherosclerosis and obesity.
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