生物信息学
抗菌肽
生物
MTT法
细胞毒性
体外
肽
细胞凋亡
癌细胞
抗菌剂
膜联蛋白
癌症
分子生物学
生物化学
微生物学
基因
遗传学
作者
Douglas Law,Ahmed Abdulkareem Najm,Jia Xuan Chong,Joelene Zi Ying K’ng,Mas Amran,Huey Lih Ching,Rui Rui Wong,May Ho Leong,Ibrahim Mahmood Mahdi,Shazrul Fazry
出处
期刊:PeerJ
[PeerJ, Inc.]
日期:2023-07-19
卷期号:11: e15651-e15651
被引量:8
摘要
experiments analysis showed that ATMP5 had the activity to inhibit the growth of the breast cancer cell line (MDA-MB-231) after 48 h and managed to arrest the cell cycle of the MDA-MB-231, apoptosis induction, and overexpression of the p53 by interaction with the related apoptotic genes. This research opened up new opportunities for developing potential and selective anticancer agents relying on antimicrobial peptide properties.
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